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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

We will use this painful adjustment on the part of government to ensure that things will be much more convenient and easier for our businesses to enhance their competiveness on the market.
However, before starting their EMBAs, there is already a wide gap in salaries, with women earning on average 15 per cent less than men, at $111,000 and $128,000 respectively.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

3. 需求弹性。解决价格低迷的方法就是低价。这是老生常谈,而且适用于供需两个方面。超低的原油价格会刺激需求复苏吗?某些国家对石油市场控制较严,低油价可能不会延伸到零售领域。印尼等国已经取消成品油补贴,这有利于国家财政,但消费者得到的实惠将减少。不过,美国汽油价格已跌破每加仑2.40美元,与2014年中期相比,降幅超过了35%。而此番降价已带动汽油消费的攀升。2014年底,美国汽油日消费量创2007年以来新高。低价可以提升需求,而需求的增长则可带动油价反弹。
亲朋好友称Ross是一个充满活力有梦想的女孩子,她走到哪里,都会被她点亮。她去世后几天,她的母亲Alicia Jesquith告诉记者,女儿突然离世,她需要一个答案。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

伦敦博蒙特·内森顾问公司(Beaumont Nathan)的联合创始人雨果·内森(Hugo Nathan)说:“新投资者对早期绘画大师的作品有兴趣,不过他们想要的是杜维恩(Duveen)卖给强盗大亨们的作品。他们想要名作。”他指的是英国艺术交易商约瑟夫·杜维恩(Joseph Duveen),他把很多伟大的艺术品带去了美国。

Graphical abstract: Soft matter science and the COVID-19 pandemic
From the themed collection: 沈城冬季“暖消费”进入小高峰
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

v. 形成(颗粒状),

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
From the themed collection: 香港推住宅空置税
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

adj. 最初的,首要的,最好的,典型的
authorization
Make sure you've got a good plan for seeing that your children are cared for when you're scheduled to be in class, and when you need to study. It really is possible to raise children while you're going to school. People do it every day.
单词elite 联想记忆:

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

欧盟外交政策高级代表费代丽卡?莫盖里尼(Federica Mogherini)和欧盟扩大事务专员约翰内斯?哈恩(Johannes Hahn)也表明立场,批评埃尔多安提议的宪法改革及其最近的言辞。
一座陵墓般的濒危物种仓库。
Fifty-two colleges and universities across 11 provinces in China are equipped with vending machines that sell AIDS detection reagent for students to conduct self-examinations.
Adapted from an online novel Queen of No.11 Agent, the TV series is about the adventure of a female slave Chu Qiao and her romance with a prince Yan Xun.

Graphical abstract: Trends and targets in antiviral phototherapy
From the themed collection: 2015橱柜十大品牌最新排名
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

你觉得《乐高蝙蝠侠大电影》是一部儿童片吗?那你就大错特错了。这部影片充满了冷幽默和好笑的段子,欢乐中带着机智。总的来说,如果你喜欢《发展受阻》里的威尔?阿奈特,那你也会喜欢这部电影。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

金发女郎乐队《花粉传播者》

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

该报道称,并没有老师和学生喝了有毒的水。
turkey

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

It's almost TOO good. Soulful and aching and grand, Adele's theme to Skyfall is stunningly performed, and gives the distinct impression that someone tried to make the ultimate James Bond theme and had the talent to back it up. History and sensuousness have elevated two songs higher than Adele's contribution, at least in our eyes, but not by much.
“我还给了他一个直言不讳的同性恋朋友,他会责备邦德,说:‘拜托,邦德,你是生活在20世纪,不是中世纪。’”

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

Czech model Petra Nemcova went for a dress in white, which featured an extremely plunging neckline and thigh-high split. Ensuring that both her lithe legs were highlighted to the max, the stunning blonde made sure all eyes were on her as she sashayed down the red carpet.
新年英文祝福语大全

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

Dachis says: 2011 saw a huge bounce for Dominos in brand enthusiasm from their brand relaunch which 2012 just couldn’t match. It’s a shame they can’t redesign their recipes every year.
Skeptics of climate change have long argued that global warming stopped around 1998, when an unusually powerful El Ni?o produced the hottest year of the 20th century. Some politicians in Washington have seized on that claim to justify inaction on emissions.
Interest in wearable technology isn’t limited to technology companies. Mercedes-Benz is porting its mobile experience to a wearable device, while Virgin Atlantic is exploring the customer service aspect of Google Glass on a trial basis. Kenneth Cole is also using Glass as part of a marketing campaign.
n. 匙,调羹,匙状物

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
From the themed collection: 顺德制订水性涂料行业标准
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

n. 姿势,态度,情形

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

Age: 44
最近两年你都没有涨薪水

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
From the themed collection: 传统家居业O2O前景尚不明朗
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

克雷·汤普森贡献19分,博古特也贡献了13分。勇士队也创下了自2002-03赛季小牛队14连胜之后的最佳开局。只需再有三场比赛的胜利,金州勇士就会追平1948-1949赛季华盛顿子弹和1993-94赛季休斯敦火箭共同创下的开局15连胜的记录。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

他说,“油价将波动上行。”

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
From the themed collection: 顺德制订水性涂料行业标准
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

拥抱世界
2014年,世界杯在1978年以后又重新回到南美的怀抱,当时,马里奥·肯佩斯(Mario Kempes)带领阿根廷队战胜了荷兰队,保持着南美球队在南美洲大陆上举行的世界杯中赢得冠军的记录。那么,2014年会有所不同吗?包括卫冕冠军西班牙队在内的欧洲诸强能够实现那些在过去的比赛中的欧洲球队未能做到的吗?抑或,有其他任何大陆能够有实力挑战强大的南美球队吗?
只有公民,而他们的选择不仅可能、而且必然会改变。
A lot of the best James Bond theme songs sound like they belong in a lounge act. That's not a complaint, just an observation. For whatever reason, the English new wave act Duran Duran was given free reign to provide A View to a Kill with a new and exciting sound all its own. "A View to a Kill" was a hit song, and it probably would have been a success even without the James Bond connection. It's entertaining and cool and energetic, and it promises one hell of a good time. (Whether or not the movie actually lives up to that promise is a matter of some debate.)

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

单词accomplished 联想记忆:
上海交易所和深圳交易所总共完成了61宗IPO交易,较2015年同期分别下滑了67%。融资总额288亿元人民币,较2015年同期分别下滑了80%。
《前第一夫人要求伊斯兰教变得宽容并支持女权》(A Former First Lady Presses On for a Tolerant, Feminist Islam)
中国国家统计局工业司何平在随后发布的数据解读声明中称,尽管石油和其他投入价格下跌支撑了利润率,但出厂价格的下跌抵消了这些利好影响。
尽管看起来有着大量的目标核对工作,但在5月7日,中国驻贝尔格莱德的大使馆却被从美国空军B-2幽灵轰炸机上发射的五枚卫星制导联合直接攻击弹药击中。三名中国记者——新华社记者邵云环,光明日报记者许杏虎和他的妻子朱颖在袭击中身亡。另外20名中国公民受伤5人伤势严重。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

WASHINGTON: Indiahas trimmed its holdings of US government securities to $77.5 billion at the end of October even as the world's largest economyis expanding at a moderate pace.
create增长,产生+ive →有创造性的

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

时报影评人曼诺拉·达吉斯(Manohla Dargis)与A·O·斯科特(A. O. Scott)分享他们挑选的年度最佳电影。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

Last year, the CPI increase peaked at 2.5 percent in January, and later fluctuated below 2 percent during the rest of the year.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

In the past six months alone, the Australian-born company fortified its senior executive ranks with high-profile hires from Amazon, PayPal, Google, and Twitter. It brokered a high-profile deal with Magento, the market leader, that promises to bring thousands of new customers to it. And it broke the lease on its new San Francisco office because it is hiring so quickly that it now needs triple the space it originally anticipated.
10月份,尽管中国出台了大量限购措施,中国新建住宅价格增速却仍然加快。
Summly and Yahoo refused to comment on the deal’s terms.
The government's next snapshot of the job market, due Friday, will be distorted by Sandy, which devastated the Northeast in late October, leaving many jobless. Economists say Sandy could temporarily knock anywhere from 100,000 to 150,000 off of the government's jobs tally for November, resulting in job growth of under 100,000 or even much less.[qh]

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

Total net profit for China’s commercial banks grew by 2.4 per cent last year, according to data from China’s bank regulator. Smaller banks saw increases in profit growth, while bigger banks slowed down.
我们可以看到时空涟漪的源头。
Despite the reported success of the Duke and Duchess of Cambridge's official visit to Canada back in September, timekeeping needs to be looked at for future trips.
Productivity is the name of the game for entrepreneurs. The good news is that there are thousands of amazing software applications out there, designed to make your life easier. The bad news is that you don’t have time to try thousands of software applications. Which ones are worth your time?

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

PwC公司的管理人员立刻意识到有问题,但一切都太迟了,他们没法纠正错误了,唐纳薇已经念出《爱乐之城》的名字,而那张卡片本来是为最佳女演员准备的。那天晚上稍早些时候,就已经宣布过爱玛?斯通因为在《爱乐之城》中的表演而获得了最佳女演员奖。
D'Aloisio himself strives to maintain a bubble of normalcy. He dates the same girl he did before the whirlwind hit. And though he's stopped attending school-he's too busy to sit in class while overseeing Summly's development-he still gets his work from his teachers and meets with them regularly. He cherishes the fact that his circle of friends knows little of his life as a budding industrialist. When I met him, he was about to head to Greece for a weeklong vacation with a pack of high school pals.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Shares in Hyundai and AmorePacific slid on Friday, down 4.4 per cent and 12.5 per cent respectively in late afternoon trading in Seoul.
Leading actress Sun Li played Zhou in the drama. Despite her age, Sun, who was born in 1982, still successfully presented a lovely and innocent teenage Zhou in the eyes of many audience members.
另一名来自美国的毕业生写道,来自世界各地的知识的丰富性和深度为课程带来了巨大的价值,他补充称,“鉴于这里汇聚着众多的文化和经验,有关贿赂的课堂道德讨论不像典型的美国学校那样枯燥。”
Chinese industrial profits slumped by a record 8 per cent last month, as Beijing’s targeted stimulus efforts failed to arrest a slowdown in the key driver of China’s economy.
But not every reporter (including this one) would agree with the final assessment.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

'Blue Jasmine' belongs, chronologically, to Woody Allen's late period of self-renewal. Artistically, however, it's a comfortable fit with some of the brightest comedies-the brightest/bleakest/wriest comedies-he's ever done. The centerpiece is Cate Blanchett's astonishing performance as Blanche duBois re-imagined to be the half-mad ex-wife of Alec Baldwin's crypto-Bernie Madoff. Not all that far from the center, Sally Hawkins, Andrew Dice Clay, Bobby Cannavale and Louis C.K., among others, maneuver their way through mine fields of deceit and disappointment.
[.h?spi't?liti]
Put succinctly, there was no way to describe or explain the crosscurrents of 2014. And I’m not convinced that the benefit of hindsight will make what happened this year any clearer years from now.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

我曾被一位CEO要求雇用一位有着乌黑长发的长腿美眉,虽然她的能力不强。还有一次,我被要求不要雇用有小孩的应聘者,因为公司已经雇用了太多为了看足球赛请假的员工。这种事经常发生。
Hurun Chairman Rupert Hoogewerf said: "Those entrepreneurs should be called 'super wealth creators' instead of simply 'rich people', which could highlight their contribution to China's society and economy."

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

中国的旅游业官员正力图在2014年扭转入境游客减少的情况,专家认为,如果能对其过时的旅行团进行改进并降低票价,这一计划就有可能实现。
The U.S. $10 bill will feature the portrait of a notable U.S. woman by 2020.
cast

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

●"Florida man dies in meth-lab explosion after lighting farts on fire"
Here are four memorable designs from the year, including commentary from some of the artists who helped shape the looks.
adj. 社团的,法人的,共同的,全体的

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

此外,城镇人口也有所增加,现在已经占到总人口的55.88%,相比2010年普查时增加了6.2%。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

但当格雷泽给我们带来《皮囊之下》,这部经过他长期酝酿的,由荷兰作家米歇尔·法柏的科幻小说改编的电影时,真是让人惊叹:欢快,不安,大胆。斯嘉丽扮演的外星人藏于人类的皮囊里,穿梭在格拉斯哥街道和商场,不亚于一位一线明星。现实生活中的路人在镜头中完美的展现,而隐身的约翰森面无表情的估算着三个地球人可被利用的热量值。接着演员带着被色诱的人类离开人群,来到她自己的地方:一个神秘的黑暗的洞穴中。在这里,情色恍惚间,人类贡献自己的肉体,被囚禁,被养殖成为食物,谁知道呢,又或许是人类的灵魂。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

The various mustaches were conceived by the designer Frances Hannon, who has built a number of facial hair styles for Bill Murray in Anderson films (“Rushmore,” “The Life Aquatic With Steve Zissou”). Here, she asked many of the actors to grow out their facial hair so she would have the option to cut it in any shape she wanted.
Grab your rolling bag, and pack your patience. The holiday air travel season is about to begin. And if you want to have a stress-free trip, the best advice we can give is to fly west.

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

By the end of 2015, Shanghai's population of migrant residents had decreased to 9.8 million, comprising 40.6 percent of the city's roughly 24 million permanent residents, according to statistics released by the Shanghai Municipal Statistics Bureau on Monday.
Americans are celebrating Columbus Day Monday.Columbus Day is a federal holiday observed on the second Monday in October, marking the anniversary of the arrival of Christopher Columbus to the Americas. Columbus, an Italian explorer sailing under the Spanish flag, led four expeditions to the New World, but never accomplished his original goal -- to find a western ocean route to Asia. Instead, Columbus ushered in a new era in world history by opening up the Americas to exploration.
《一位德国女权主义先锋在痛苦中回顾过去》(A Pioneering German Feminist Looks Back in Anguish)
n. 综合症,典型表现

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

2016年度的《胡润百富榜》显示,姚振华的净财富去年涨了逾8倍,至172亿美元,他也因此成为中国的第四大富豪。去年他的排名是第204位。
Global emissions of greenhouse gases jumped 2.3 percent in 2013 to record levels, scientists reported Sunday, in the latest indication that the world remains far off track in its efforts to control global warming.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

adj. 推测的,推理的,思索的,投机的
从10年和20年的时间跨度来看,地域和资产类别的多元化已经证明对投资回报和风险管理有益。不幸的是,在12个月内,不一定能看到此种战略的好处。在如今这个140字微博消息和2分钟短视频盛行的时代,投资者不能以长期的表现来判断其投资组合的成败,又有何奇怪?

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

007系列电影主题曲第八名:南希·辛纳查--《你只能活两次》

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

The report said families back home receive an average of $200 a month, which makes up 60 percent of the household income.Using the steady flow of remittances, families can buy food, get housing, go to school, access healthcare, improve sanitation, or even invest in a business and have some savings, the report said.
10月中国进口同比下降18.8%,降幅较9月的20.4%略有改善。石油和其他大宗商品价格大幅走低也帮助压低了进口总值。
The data was released to encourage the adoption of stronger passwords. Mr Slain added:"As always, we hope that with more publicity about how risky it is to use weak passwords, more people will start taking simple steps to protect themselves by using stronger passwords and using different passwords for different websites."
PPI已连续下降44个月,反映出建房材料和原料的供应过剩,以及重工业的产能过剩。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

拍卖行称这次拍卖会还将拍卖两颗超过100克拉的钻石,吸引了30多个国家的买家。
在过去的二十年里,几起校园中毒事件引发了群众对学生心理发展及帮助的争论和关注。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

Lady Gaga凭她的非营利性的天生如此的慈善基金会名列第四名。
中国早已超越了俄罗斯成为紧随美国之后的世界第二大强国。
That pushed the state share of total investment for the year to date down marginally to 36.6 per cent, still the largest share since 2011 and reflecting the outsize role of government spending in sustaining economic growth during 2016.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

自动驾驶汽车,自拍杆,无人驾驶飞机,触屏设备,电子香烟,喷射背包和许多其他看起来像现代的发明的东西,其实都是老发明。大部分的"发明者"把它们当做新发明,甚至去申请专利。但事实是,这些"发明"已经存在一段时间了。它们都有早期类似的原型,这些早期产品最终没有投入生产,或因为特定原因而限量生产。而有些"发明"得以大批量生产,却因为销售不佳而流产。
Total net profit for China’s commercial banks grew by 2.4 per cent last year, according to data from China’s bank regulator. Smaller banks saw increases in profit growth, while bigger banks slowed down.
During last year's LFW, there were 250 anti-fur protesters, The Guardian reported, and a show in February saw an activist storm the stage at a Mary Katrantzou show.

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

Dwight Howard
"Sydney's housing prices shot up because foreign investors are buying trophy assets, in places like Bondi," says Elliot.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

Plum Alley:
8. Software engineer
据Digitimes的消息,更大尺寸的iPhone 6将采用“台积电(TSMC)生产的20纳米处理器”。此前曾有报道称,新款iPhone的屏幕尺寸将和三星Galaxy 4的屏幕一般大小(不到5英寸)。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

n. 学会,学院,协会
6. Ipoh, Malaysia-Around 200 kilometers north of Kuala Lumpur, the former British colonial city is now a foodie destination, where local street food and boutique cafes around.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

美国就业市场笼罩着重重阴云──特别是遭遇增税、减支双重打击的可能性,即“财政悬崖”。[qh]
Caleb Rogers is one of two people facing legal action from gaming studio Epic Games for using cheat software to play the game Fortnite.
10. Michelle Jenneke

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

Will the S&P 500 finish the year above 2,650

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
From the themed collection: 巧算家装涂料用量 防欺骗防浪费
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

交通银行首席经济学家连平表示,不断上涨的生产者物价可能会在较长的时间内推高消费价格。
Some hits have gone so far over the top they should be winded, yet instead keep on puffing gusts of hot air, including “Downton Abbey,” “Scandal” and “Revenge.” A new addition on ABC, “How to Get Away With Murder” was a fun substitute, a lurid nighttime soap opera about lawbreaking defense lawyers — “Law & Disorder.”

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

For now, occasional high-ticket deals such as the Dah Sing Financial Centre and the purchase of a HK$2.1bn luxury house on the affluent Peak, come amid wider pessimism about the sector. The office sector showed the most activity in the first quarter this year, but this still translated into only eight deals in total, according to CBRE.
单词calendar 联想记忆:

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
From the themed collection: 浙民投与佳兆业“生化”危机再起
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

土耳其外交部愤怒地驳斥了欧盟的批评。它说:“欧盟应该意识到,这种声明助长了极端主义,比如仇外和反土耳其情绪,因为它对避免过分言论和行动以免局势进一步恶化的呼吁,针对的只是土耳其,而不是所有违反外交公约和国际法、从而导致了这种局面的国家。”
ex出+panse扩展+ion表名词,“动作或状态 ”→扩张

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

Lei Jun, founder and chairman of Chinese smartphone giant Xiaomi Corp, agreed, describing the win as a breakthrough in artificial intelligence.
全球重量级的央行家和政府官员周六表示,对一些新兴经济体脆弱性的担忧以及近期金融市场的剧烈波动,应该不会挫伤人们对今年全球经济形势的“谨慎乐观”态度。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

节目15 歌曲《甲板上的马头琴》,王宏伟

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
From the themed collection: 广州:公租房可“柔性退出”
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

只有资产管理公司利润出现上升,同比增长16.64%,至37.17亿元人民币。
New Year's greetings and best wishes!
According to a report by Beijing Statistics Bureau, retail sales of consumer goods in the Chinese capital surpassed 1 trillion yuan ($152 billion) in 2015, up 7.3 percent year on year.
The 60-episode TV drama was adapted from a novel Legend of Princess Pearl published in 2007. It focuses on the protagonist Shen Zhenzhu’s romance with her husband and their efforts to protect the country.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

Australia is the No. 8 Best Country overall. The Land Down Under – No. 4 in Quality of Life and No. 9 in Adventure – also ranks in the top 10 in terms of education.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

We asked the Dachis Group, a social media measurement agency, to tell us which brands got the biggest increases in consumer love, and which lost the most ground.
unemployment
日前,美国民主党候选人希拉里·克林顿承诺,如果她在总统竞选中获胜,那么她的内阁将有半数成员是女性。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

Song “Super Shero”(S.H.E.)
Miranda Lambert “Bathroom Sink” (RCA Nashville)

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
From the themed collection: 并购终止 佛山照明剧烈波动
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

其他人将想方设法利用技术来帮助人们减少上网时间。谷歌(Google)前雇员特里斯坦哈里斯(Tristan Harris)发起的“时光莫虚度”(Time Well Spent)运动正在吸引人气,该运动鼓励设计者理解他们所控制的微妙的心理力量,以解决其所称的“数字注意力危机”。据Recode报道,曾经在Pinterest和Facebook工作的蒂姆肯德尔(Tim Kendall),计划成立一家专注于对抗设备上瘾的初创公司。
大约一千八百万人,想要得到一个好的全职工作,但却没能找,这一数字在金融危机过后五年半左右的恢复时间中是高得不寻常的,而且尽管失业时间在半年及以上的人数大幅下降,然而这个数字仍然比2007年7月金融危机发生之前的任何时候都要高。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
From the themed collection: 新型城镇化规划 引建材股大涨
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

adj. 社会的,社交的

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

TextPride was a fine business, but a tiny one. Meanwhile, the market for messaging apps was exploding. Facebook FB 0.61% bought WhatsApp for $19 billion; that service now has 700 million monthly active users. Tango, an app with 250 million registered users, is worth $1.5 billion. Kik has 200 million registered users. Snapchat, worth $10 billion, has 100 million users. A new study, commissioned by Kik, shows that U.S. users now spend more time on average in messaging apps than they do on social networking apps. The only problem? These messaging apps need ways to make money, and there’s no reasonable way for advertisers to wedge themselves into conversations between friends.
But the economic base for these capabilities is steadily declining.
Theresa May is still facing resistance from within her own party. Vince Cable, the Liberal Democrats’ sage and leader, still thinks Brexit may not really happen.

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

美国时间上周日,乡村音乐界的大牌们齐聚拉斯维加斯,出席2013年乡村音乐学院奖颁奖典礼。
第三步 练习古怪表情
The Big Sick
今年中国内地共有54所高校进入亚洲大学排行榜前300名。

Graphical abstract: Length-scale dependence of protein hydration-shell density
From the themed collection: 过百城市松绑 一二线楼市待升
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

Volatility in currency markets is also likely to be a factor for agricultural commodity prices in the next 12 months, with the euro likely to depreciate as a result of French, Dutch and German elections, Rabobank reckons.
Rouslan Krechetnikov和Hans Mayer对液体的溅出现象进行了研究。他们考察的课题是:人们在端着咖啡杯走动时咖啡的溅出情况,给你个提示吧,在你走到第七步至第十步之间,咖啡最容易溅出。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

Latest data from the US Treasury Department shows that India held securitie sworth $80 billion in September and further reduced its exposure to $77.5billion in October -- which is also a three-month low.
During the summers, Good Humor ice cream trucks visit the company's campuses every other Friday during lunchtime. In the fall, cider and doughnuts are served twice a month, mid-morning.
不过,在交易商的仓库里和收藏家的脑海里还有大量早期绘画大师的作品,它们的要价仍停留在汤米·库珀那个年代。不幸的是,在如今的市场上,以那样的价格,很多画作都将像被小提琴砸了个大洞的斯特拉迪瓦里画作一样卖不出去。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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Despite such arguments from a handful of scientists, the vast majority of those who study the climate say the earth is in a long-term warming trend that is profoundly threatening and caused almost entirely by human activity.
蕾哈娜在榜单上排名第二,获得亚军,《男人装》表示:在这12个月以来,她真是无处不在,但是我们依然没有对她审美疲劳。

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